After a young boy is almost runover by a maniac on a highway, a re-encounter and confrontation by the boy's father with the driver sets off conflicts with a carful of maniacs.
Cocky researcher Sebastian Caine is working on a project to make living creatures invisible. Determined to achieve the ultimate breakthrough, Caine pushes his team to move to the next phase — using himself as the subject. The test is a success, but when the process can't be reversed and Caine seems doomed to future without flesh, he starts to turn increasingly dangerous.